Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online:: 21446
ORIGINAL ARTICLE
Year : 2016  |  Volume : 19  |  Issue : 2  |  Page : 59-62

A comparison of carotid intimal thickness and other risk factors in patients with prediabetes and normoglycemic subjects in the Eastern India


1 Department of Medicine, College of Medicine and JNM Hospital, Kalyani, Nadia, India
2 Department of Medicine, ESIC Hospital, Joka, West Bengal, India
3 Department of Medicine, R. G. Kar Medical College, Kolkata, West Bengal, India

Correspondence Address:
Somak Kumar Das
A/14, 2nd Floor, Katjunagar, Jadavpur, Kolkata - 700 032, West Bengal
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1118-8561.186040

Rights and Permissions

Introduction: Prediabetes is a precursor to diabetes; it is an intermediary state between normoglycemia and hyperglycemia. This metabolic state keeps company with major risk factors for atherovascular disease. The risk of coronary artery disease (CAD), including myocardial infarction, is higher in prediabetes patients compared to normal population. Aim: The aim of this study is to assess the prevalence of prediabetes in the patients with CAD and to compare the glycemic status, carotid intimal thickness (CIMT) and other risk factors in the prediabetes patients and normoglycemic subjects. Materials and Methods: One-hundred and fifty CAD patients and 80 control subjects who were age and sex matched were studied. Fasting blood glucose, a 2 h glucose tolerance test and CIMT were compared in both groups. Results: Mean age in the control group was 59.93 ± 10.84 years whereas it was 61.0 ± 11.02 years in the CAD. The mean CIMT was more and statistically significant in the case group. Impaired fasting glucose (IFG) was found in 30 (20%) cases and impaired glucose tolerance (IGT) was found in 45 (30%) cases, and both IFG and IGT were found in 12 (8%) cases. The prevalence of prediabetes in this study was 58%. Nondiabetic CAD patients had statistically higher fasting glucose level, 2-h oral glucose tolerance test values, total cholesterol and very low density lipoprotein levels than control patients. Conclusion: These findings stress the need for early screening and management of prediabetes preventing further progression to diabetes and CAD, even in rural patients.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed3724    
    Printed229    
    Emailed0    
    PDF Downloaded258    
    Comments [Add]    

Recommend this journal