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Year : 2000  |  Volume : 3  |  Issue : 2  |  Page : 69-73

Paraplegia in prostate cancer

26 Old Aba Road, Port Harcourt, Rivers State, Nigeria

Correspondence Address:
Eke Ndubuisi
26 Old Aba Road, Port Harcourt, Rivers State
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Source of Support: None, Conflict of Interest: None

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A retrospective study of patients treated for paraplegia and prostate cancer in Port Harcourt is presented together with a review of the Literature. Six patients presented with 7 episodes of paraplegia. Of these, 3 e pisodes of paraplegia occurred in 2 patients who were on hormonal therapy for advanced prostate cancer Four patients presented with paraplegia and were found to have prostate cancer. The patients aged 58-72 years. The histological diagnosis included we / /-differentiated, poorly-differentiated and anaplastic types. The duration of spinal cord compression prior to paraplegia was 3 weeks to 5 months. The diagnosis was made from digital rectal examination (DRE), X-rays and prostate bi op. v. The treatments were bilateral subcapsular orchidectomy (BSO ) and diethylstilbestrol. One patient with quadriplegia remainsambulantfor 3 years. One patient was ambulant for 2 years until the recurrent paraplegia. In the 3 episodes already being treated, the patient died within one month of paraplegia. In 5 e pisodes in 4 patients, there was no significant response to treatment. results compare favourably with those elsewhere. Bilateral subcapsular orchidectomy su pplemented diethylstilbestrol is justified in patients with paraplegia from prostate cancer.

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