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Year : 2004  |  Volume : 7  |  Issue : 1  |  Page : 41-45

Post-operative evaluation of anterior pituitary function in a Nigerian with hyperprolactinaemia: A case report and review of literature

1 Departments of Chemical Pathology ABU Teaching Hospital, Zaria, Nigeria
2 Departments of ABU Teaching Hospital, Zaria, Nigeria

Correspondence Address:
H S lsah
Departments of Chemical Pathology ABU Teaching Hospital, Zaria
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Source of Support: None, Conflict of Interest: None

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Prolactinoma is an endocrine abnormality associated with hy perprolactinaemi a of which there is paucity of data in t his environment probably due to under-re porting , under diagnosis and inadequate skill for management . This is a report of a 42 year old Nigerian w ho underwent surgery for pituitary prolactinoma in Western Germa n y and was referred to our hospital for assessment ,of an t erior pituitary reserve on return to Nigeria. Basal values of glucose , cortisol, T3 , 14 , TSH , LH , FSH , and prolactin were measured following which a triple function test was conducted by intravenous administration of a bolus consist ing of ug of ACTH, 200ug TRH and lOOug GnRH . Basal values demonstrated normoglycaemia and euthyroid i sm while responses to TRH and GnRH indicated rest oration of anterior pituitary capacity for synthesis and control of TSH , LH , FSH and prolactin post-operatively .

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