| ORIGINAL ARTICLE |
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| Year : 2014 | Volume
: 17
| Issue : 4 | Page : 125-127 |
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Comparison of echocardiographic parameters among patients with pulmonary hypertension treated with statin and those without
Mohammed Almansori
Department of Medicine, Division of Cardiology, University of Dammam, Dammam, Saudi Arabia
Correspondence Address:
Mohammed Almansori
Department of Medicine, Division of Cardiology, University of Dammam, P. O. Box 12875, Dammam 31483
Saudi Arabia
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/1118-8561.146813
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Introduction: Pulmonary hypertension is a progressive disease where endothelial dysfunction plays an important role in its etiology. Statins have been considered a therapeutic option for pulmonary hypertension due to their pleiotropic effects. Materials and Methods: We investigated the association between statin use and echocardiographic parameters in 73 patients with pulmonary hypertension (23 patients were on statin and 50 patients were not taking statin). Results: Our study showed no association between statin use and different echocardiographic parameters used to evaluation pulmonary hypertension though there was a trend toward less right ventricular dilatation favoring the statin group (25.20 ± 14.7 mm vs. 29.7 ± 9.5) with a P = 0.052. Conclusion: We observed noassociation between statin use and echocardiographic findings in patients with pulmonary hypertension. A larger scale studies are need to confirm our findings. |
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