Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Home Print this page Email this page
Users Online:: 384
ORIGINAL ARTICLE
Year : 2022  |  Volume : 25  |  Issue : 2  |  Page : 47-51

Association between hormonal contraceptive use and derangement of lipid profile among women attending Muhoza Health Center, Rwanda


Department of Biomedical Laboratory Sciences, INES Ruhengeri Institute of Applied Sciences, Musanze, Rwanda

Correspondence Address:
Dr. Callixte Yadufashije
Department of Biomedical Laboratory Sciences, INES Ruhengeri Institute of Applied Sciences, Musanze
Rwanda
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/smj.smj_70_20

Rights and Permissions

Background: Contraception is a method used to prevent unwanted pregnancies and child spacing. Although the method is beneficial in over birth control and stabilization of population explosion, the hormonal components of used drugs have been shown to generate many sides' effects among users. Aim and Objective: This study was conducted to investigate the effect of hormonal contraceptives (HCs) on lipid profile among women attending family planning services at Muhoza Health Center, Rwanda. Materials and Methods: This was a cross-sectional study and purposive sampling was used to select study participants among HC users, although simple random sampling was used to select study participants of nonusers. A total of 88 participants were recruited and among them, 57 were HC users, while 31 were nonusers known as controls. Blood sample was collected after the consent of the participant accepting to participate in the study. Collected blood samples were analyzed to evaluate parameters of the lipid profiles, including high-density lipoprotein (HDL), triglycerides (TG), total cholesterol (TC), and low-density lipoprotein (LDL) by using Humalyzer plus at INES-Ruhengeri clinical biochemistry laboratory. Results: Findings of this study show a high risk of developing abnormal lipid profile among the exposed group compared to controls. Association was found in LDL-cholesterol (LDL-C) (odds ratio [OR] = 11 > 1), TC (OR = 14 > 1) and TG (OR = 2.8 > 1). The high risk of developing abnormal lipid profile among users compared to controls was observed in LDL-C and TC. HDL-cholesterol (OR = 0.8 < 1) showed that there is no risk of developing abnormal lipid profile among users and controls. Implant (χ2 = 10, df = 3, P = 0.018397 < 0.05) was statistically significant to affect all studied lipid profile parameters while TC (χ2 = 20.88, df = 3, P = 0.000111 <0.05) was statistically significant to be affected by all HCs studied among users. Conclusion: Lipid profile is affected by HCs among users. Most of the studied lipid profile parameters were seen to be affected by HC use. HC users should be followed up as dyslipidemia could lead to different health conditions.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1019    
    Printed50    
    Emailed0    
    PDF Downloaded136    
    Comments [Add]    

Recommend this journal